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[化疗期间破坏性肺结核患者血液中铜、锌水平及其相关金属酶活性的作用与变化]

[The role of and changes in the copper and zinc levels and the activity of their related metalloenzymes in the blood of patients with destructive pulmonary tuberculosis during chemotherapy].

作者信息

Zozuliak V I

出版信息

Lik Sprava. 1995 May-Jun(5-6):97-100.

PMID:8630826
Abstract

Patients in acute phase of destructive pulmonary tuberculosis experienced a considerable rise in the activities of ceruloplasmin and carboangidrase as well as in the content of copper and zinc. In so far as destructive pulmonary tuberculosis is concerned, the therapeutic results were far from being gratifying. Loss of copper and zinc arising in the organism rapidly lead to a depletion of the latter and deficiency of trace elements, which fact may, in its turn, disturb the work of the compensatory-defense mechanisms. This warrants correction of the above trace elements in the organism of a patient with destructive pulmonary tuberculosis.

摘要

在浸润型肺结核急性期,患者血浆铜蓝蛋白、碳酸酐酶活性及铜、锌含量显著升高。就浸润型肺结核而言,治疗效果远不尽人意。机体铜、锌流失迅速导致其耗竭及微量元素缺乏,这反过来又可能干扰代偿防御机制的正常运作。因此,对浸润型肺结核患者机体的上述微量元素进行纠正很有必要。

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