Shibuya H, Wakita T, Nakagawa T, Fukuda H, Yasumoto M
Department of Radiology, Tokyo Medical and Dental University, Japan.
Cancer. 1995 Jul 1;76(1):101-5. doi: 10.1002/1097-0142(19950701)76:1<101::aid-cncr2820760115>3.0.co;2-d.
The relation between esophageal cancers and head and neck tumors was studied in order to improve the treatment results in patients with multiple cancers.
We reviewed the records of 3,375 patients with an indexed squamous cell carcinoma of the head and neck treated at our institution between 1960 and 1994; and 81 patients were found to have an associated esophageal carcinoma. Similarly, the records of 434 patients with an indexed esophageal cancer were reviewed; and 54 patients had cancers in other organs or in the residual esophagus. A total of 135 esophageal cancers with 154 synchronous or metachronous cancers were entered into the analysis.
The risk of developing esophageal cancer was ten times higher in male patients with head and neck cancer than in female patients. Synchronous or metachronous esophageal cancer associated with head and neck cancer was most frequently seen with pharyngeal cancer (28/360 = 7.8%), followed by in the oral cavity (47/2148 = 2.2%).
Better knowledge of the relation between an esophageal cancer and a head and neck cancer may lead to the early detection of subsequent small, potentially curable neoplasms sited in either the esophagus or the head and neck region.
为了改善多发癌患者的治疗效果，对食管癌与头颈部肿瘤之间的关系进行了研究。
我们回顾了1960年至1994年间在我院接受治疗的3375例索引性头颈部鳞状细胞癌患者的记录；发现81例患者伴有食管癌。同样，回顾了434例索引性食管癌患者的记录；54例患者在其他器官或残留食管中有癌症。共有135例食管癌及154例同步或异时性癌纳入分析。
头颈部癌男性患者发生食管癌的风险比女性患者高10倍。与头颈部癌相关的同步或异时性食管癌最常见于咽癌（28/360 = 7.8%），其次是口腔癌（47/2148 = 2.2%）。
更好地了解食管癌与头颈部癌之间的关系可能有助于早期发现随后位于食管或头颈部区域的小型、潜在可治愈的肿瘤。
