Holcomb G W, Tomita S S, Haase G M, Dillon P W, Newman K D, Applebaum H, Wiener E S
Childrens Cancer Group, Arcadia, California, USA.
Cancer. 1995 Jul 1;76(1):121-8. doi: 10.1002/1097-0142(19950701)76:1<121::aid-cncr2820760119>3.0.co;2-#.
The safety and efficacy of minimally invasive oncologic procedures in children have not been well defined and only limited anecdotal experience has been published.
A retrospective review of all patients undergoing either a laparoscopic or thoracoscopic procedure at Childrens Cancer Group institutions between December 1, 1991, and October 1, 1993, was performed.
Eighty-five children underwent 88 minimally invasive surgical procedures as part of the evaluation or treatment for cancer at 15 participating centers. In 25 patients, laparoscopy was performed and 60 patients underwent 63 thoracoscopic operations. Tissue biopsies were taken in 67 cases and diagnostic material was obtained in 99% of the biopsies. Seven complications occurred, all within the thoracoscopic group. These included conversion of six operations to an open procedure. One patient developed atelectasis postoperatively.
In pediatric patients with suspected cancer, laparoscopy was highly accurate with minimal morbidity; thoracoscopy was nearly as efficient with slightly higher morbidity. Both modalities are useful for assessment of resectability, for staging purposes, and for evaluation of recurrent or metastatic disease.
儿童微创肿瘤手术的安全性和有效性尚未得到明确界定,仅有有限的轶事性经验被发表。
对1991年12月1日至1993年10月1日期间在儿童癌症研究组机构接受腹腔镜或胸腔镜手术的所有患者进行回顾性研究。
85名儿童在15个参与中心接受了88例微创外科手术,作为癌症评估或治疗的一部分。25例患者接受了腹腔镜检查,60例患者接受了63例胸腔镜手术。67例进行了组织活检,99%的活检获得了诊断材料。发生了7例并发症,均在胸腔镜组。其中包括6例手术转为开放手术。1例患者术后发生肺不张。
在疑似患有癌症的儿科患者中,腹腔镜检查准确性高,发病率低;胸腔镜检查效率相近,但发病率略高。两种方法都有助于评估肿瘤的可切除性、进行分期以及评估复发或转移性疾病。