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机器人辅助腹腔镜手术治疗小儿肿瘤:双中心经验

Robotic-assisted laparoscopic surgery for pediatric tumors: a bicenter experience.

作者信息

Meignan P, Ballouhey Q, Lejeune J, Braik K, Longis B, Cook A R, Lardy H, Fourcade L, Binet Aurélien

机构信息

Service de chirurgie viscérale pédiatrique, Hôpital de Clocheville-CHU de TOURS, 49 boulevard Béranger, 37044, Tours Cedex, France.

Service de chirurgie viscérale pédiatrique, Hôpital des Enfants, 8 avenue Dominique Larrey, 87042, Limoges Cedex, France.

出版信息

J Robot Surg. 2018 Sep;12(3):501-508. doi: 10.1007/s11701-017-0773-2. Epub 2017 Dec 29.

Abstract

Mini-invasive surgery is more and more integrated in pediatric surgery. The robotic-assisted surgery brought new advantages from which the patient and the surgeon could benefit compared to laparoscopy. Its use in oncological surgery is still controversial. 12 robotic-assisted tumor resections with the da Vinci Surgical Robot (Intuitive Surgical, Sunnyvale, CA) were attempted in 11 children (mean age 7.65 years; age range 0.75-16.75 years; mean weight 30.3 kg; weight range 8.6-62 kg) in two centers. Mean total operative time was 145 min (range 72-263 min). 1 procedure (8.3%) was converted. The pathology included renal tumors (n = 2; one nephroblastoma, one metanephric adenoma), adrenal tumors (n = 9; three neuroblastomas, two pheochromocytomas, two adrenocortical adenomas, one cystic lymphangioma, one paraganglioma) and a pancreatic tumor (n = 1; one pancreatic cyst). 4 tumors (33.3%) were malignant. Every patient underwent a R0 resection. 1 child (8.3%) developed a post operative complication. Mean length of hospitalization was 3.0 days (range 2-5 days). Followup averaged 3.3 years with no recurrence. All children are alive. Robot-assisted MIS seems to be safe and feasible in pediatric tumors. The oncological surgical principles were respected in our series with low morbi/mortality and good long-term results. Robotic surgery and its technical advantages bring potential benefits for children with cancer. It has a role to play in pediatric oncological surgery but its place and indications still need to be better defined.

摘要

微创手术在小儿外科中的应用越来越广泛。与腹腔镜手术相比,机器人辅助手术带来了新的优势,患者和外科医生都能从中受益。其在肿瘤外科手术中的应用仍存在争议。在两个中心,对11名儿童(平均年龄7.65岁;年龄范围0.75 - 16.75岁;平均体重30.3千克;体重范围8.6 - 62千克)尝试进行了12例使用达芬奇手术机器人(直观外科公司,加利福尼亚州桑尼维尔)的机器人辅助肿瘤切除术。平均总手术时间为145分钟(范围72 - 263分钟)。1例手术(8.3%)中转开腹。病理类型包括肾肿瘤(n = 2;1例肾母细胞瘤,1例后肾腺瘤)、肾上腺肿瘤(n = 9;3例神经母细胞瘤,2例嗜铬细胞瘤,2例肾上腺皮质腺瘤,1例囊性淋巴管瘤,1例副神经节瘤)和1例胰腺肿瘤(n = 1;1例胰腺囊肿)。其中4例肿瘤(33.3%)为恶性。每位患者均接受了R0切除。1名儿童(8.3%)出现术后并发症。平均住院时间为3.0天(范围2 - 5天)。随访平均3.3年,无复发。所有儿童均存活。机器人辅助微创手术在小儿肿瘤手术中似乎是安全可行的。在我们的系列研究中,肿瘤外科手术原则得到遵循,发病率/死亡率较低,长期效果良好。机器人手术及其技术优势为癌症患儿带来了潜在益处。它在小儿肿瘤外科手术中具有一定作用,但其地位和适应证仍需进一步明确。

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