Carrington C B
Ann Intern Med. 1979 Apr;90(4):496-9. doi: 10.7326/0003-4819-90-4-496.
The acute lesion in Legionnaires' disease pneumonia is an acute fibrinopurulent bronchopneumonia in which the alveoli are filled with many neutrophils and macrophages and abundant fibrin. There is only slight necrosis. Although characteristic, the lesion is not specific for this agent. However, the association with this lesion of myriad small pleomorphic rods, which stain well with Dieterle's silver-impregnation method but poorly or not at all with Gram-type stains, is uncommon except in Legionnaires' disease pneumonia. Final diagnosis requires isolation of the organism or immunofluorescent studies of the tissue, sera or both. The full spectrum of the pneumonia is not known, but organization has been reported once. No definite anatomic correlate for the extrathoracic manifestations of Legionnaires' disease has been identified nor has the organism been found at extrathoracic sites.
军团菌病肺炎的急性病变是一种急性纤维蛋白脓性支气管肺炎，其中肺泡充满许多中性粒细胞、巨噬细胞和丰富的纤维蛋白。仅有轻微坏死。虽然该病变具有特征性，但并非该病原体所特有。然而，除了军团菌病肺炎外，与无数小的多形性杆菌相关的这种病变并不常见，这些杆菌用迪特尔银染色法染色良好，但用革兰氏染色法染色不佳或根本不着色。最终诊断需要分离出病原体或对组织、血清或两者进行免疫荧光研究。肺炎的全貌尚不清楚，但曾有过机化的报道。尚未确定军团菌病胸外表现的确切解剖学关联，在胸外部位也未发现该病原体。
