Hartgrink H H, Lagaay M B, Spaander P J, Mulder H, Breslau P J
Department of Surgery, Red Cross Hospital, The Hague, The Netherlands.
Eur J Surg Oncol. 1995 Dec;21(6):609-12. doi: 10.1016/s0748-7983(95)95219-5.
Eight patients with a carcinoid tumour of the breast were treated between 1985 and 1992. All were reviewed for their history, physical examination, mammographic and ultrasound features. Staining methods according to Grimelius, with H&E and Neurone Specific Enolase were repeated, and all were positive. In only one patient was a positive axillary lymph node found. No recurrences were seen during follow-up. In agreement with the available literature there seems to be a less aggressive behaviour of carcinoid tumours of the breast in patients over 65 years of age. When a carcinoid tumour is suspected in this age group, the diagnosis can be confirmed by (immuno)histological analysis of a needle biopsy. If the diagnosis of carcinoid is confirmed, a limited operation, without an axillary lymph node dissection, may be considered.
1985年至1992年间，对8例乳腺类癌患者进行了治疗。对所有患者的病史、体格检查、乳房X线和超声特征进行了复查。重复采用Grimelius染色法，同时进行苏木精-伊红（H&E）染色和神经元特异性烯醇化酶染色，结果均为阳性。仅1例患者发现腋窝淋巴结阳性。随访期间未见复发。与现有文献一致，65岁以上患者的乳腺类癌似乎侵袭性较小。当在这个年龄组怀疑为类癌时，可通过针吸活检的（免疫）组织学分析来确诊。如果类癌诊断得到证实，可考虑进行有限手术，而不进行腋窝淋巴结清扫。
