Castellino R A, Hilton S, O'Brien J P, Portlock C S
Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Radiology. 1996 Apr;199(1):129-32. doi: 10.1148/radiology.199.1.8633134.
To analyze incremental information derived from routinely obtained chest computed tomographic (CT) scans compared with chest radiographs in newly diagnosed non-Hodgkin lymphoma and the effect of this information on staging and therapy.
Abnormalities on chest radiographs and CT scans obtained at specific sites were prospectively identified in 181 consecutive patients with no previous treatment. When discrepant information was found, the effect on staging and treatment was determined.
CT and chest radiographic findings were negative in 99 (55%) patients. CT findings were positive and chest radiograph findings were negative in 17 (9%). Both chest radiograph and CT findings were positive in 65 (36%) patients, 16 with identical sites of disease and 49 with more extensive intrathoracic disease at CT. Most stage changes occurred in the diffuse large cell histologic subtype.
Although routine chest CT findings increased stage of disease in some patients, it had no effect on initial treatment of newly diagnosed non-Hodgkin lymphoma at this institution.
分析新诊断的非霍奇金淋巴瘤患者中，与胸部X线片相比，常规获取的胸部计算机断层扫描（CT）扫描所获得的增量信息，以及该信息对分期和治疗的影响。
前瞻性地确定了181例未经治疗的连续患者在特定部位的胸部X线片和CT扫描异常情况。当发现不一致的信息时，确定其对分期和治疗的影响。
99例（55%）患者的CT和胸部X线片检查结果均为阴性。17例（9%）患者CT检查结果为阳性而胸部X线片检查结果为阴性。65例（36%）患者的胸部X线片和CT检查结果均为阳性，其中16例疾病部位相同，49例CT显示胸腔内疾病范围更广。大多数分期变化发生在弥漫大细胞组织学亚型中。
尽管常规胸部CT检查结果在一些患者中增加了疾病分期，但对该机构新诊断的非霍奇金淋巴瘤的初始治疗没有影响。
