Hopper K D, Diehl L F, Lesar M, Barnes M, Granger E, Baumann J
Department of Radiology, F. Edward Herbert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Md.
Radiology. 1988 Oct;169(1):17-22. doi: 10.1148/radiology.169.1.3420256.
One hundred seven consecutive new cases of Hodgkin disease were evaluated with chest radiography and computed tomography (CT) for initial staging. The data were evaluated with regard to five popular treatment protocols for Hodgkin disease. Thoracic CT scans were normal in 30 of 31 patients who had normal radiographs. In the remaining 76 patients, CT demonstrated 194 new sites of disease and disproved 25 suspected sites of disease. The use of CT scans changed the staging of disease in 20 patients, 16 of whom had extranodal extension. The effect of using CT findings on treatment depended on whether radiation therapy was used, and, if so, which treatment protocol was followed. The use of CT findings would have changed the treatment in 6.5%-62.7% of new cases of Hodgkin disease. The authors recommend that CT scans be obtained in all patients with Hodgkin disease, especially those with abnormal chest radiographs.
对107例连续的新发霍奇金病病例进行了胸部X线摄影和计算机断层扫描（CT）以进行初始分期。根据五种常用的霍奇金病治疗方案对数据进行了评估。在31例胸部X线片正常的患者中，30例的胸部CT扫描结果正常。在其余76例患者中，CT显示了194个新的病灶部位，并排除了25个疑似病灶部位。CT扫描的使用改变了20例患者的疾病分期，其中16例有结外扩展。使用CT检查结果对治疗的影响取决于是否使用放射治疗，以及如果使用，遵循哪种治疗方案。使用CT检查结果会使6.5%-62.7%的新发霍奇金病病例的治疗发生改变。作者建议对所有霍奇金病患者进行CT扫描，尤其是胸部X线片异常的患者。
