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溃疡性结肠炎中的发育异常:放射检查足以用于诊断吗?

Dysplasia in ulcerative colitis: is radiography adequate for diagnosis?

作者信息

Matsumoto T, Iida M, Kuroki F, Nakamura S, Yao T, Okada M, Iwashita A, Fuchigami T, Fujishima M

机构信息

Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

出版信息

Radiology. 1996 Apr;199(1):85-90. doi: 10.1148/radiology.199.1.8633177.

DOI:10.1148/radiology.199.1.8633177
PMID:8633177
Abstract

PURPOSE

To determine to usefulness of barium enema examination in detecting dysplasia in patients with ulcerative colitis.

MATERIALS AND METHODS

Radiographic findings of 22 areas of dysplasia in 10 patients (seven men, three women; aged 34-81 years at diagnosis) were reviewed. Serial changes in radiographic features of four areas of dysplasia in three patients were retrospectively investigated.

RESULTS

Fourteen of 22 areas of dysplasia were shown on radiographs. Dysplasia in the rectum or sigmoid colon was depicted less frequently than that in other segments of the colon. Radiographic features were classified as obvious nodular protrusions (seven lesions), irregular mucosa (five lesions), or nodular protrusions with irregular mucosa (two lesions). Six of the seven areas of dysplasia shown as irregular mucosa were accompanied by minute spiculations in the margin of the colonic lumen. There was no correlation between radiologic features and histologic grade of dysplasia.

CONCLUSION

Barium enema examination may be used as a complementary method of cancer surveillance with endoscopy. These methods show about two-thirds of lesions associated with dysplasia.

摘要

目的

确定钡剂灌肠检查在检测溃疡性结肠炎患者发育异常方面的效用。

材料与方法

回顾了10例患者(7名男性,3名女性;诊断时年龄34 - 81岁)22处发育异常区域的影像学表现。对3例患者4处发育异常区域的影像学特征的系列变化进行了回顾性研究。

结果

22处发育异常区域中有14处在X线片上显示。直肠或乙状结肠的发育异常比结肠其他节段的显示频率低。影像学特征分为明显的结节状突出(7处病变)、不规则黏膜(5处病变)或伴有不规则黏膜的结节状突出(2处病变)。显示为不规则黏膜的7处发育异常区域中有6处伴有结肠腔边缘的微小毛刺样改变。影像学特征与发育异常的组织学分级之间无相关性。

结论

钡剂灌肠检查可作为内镜癌症监测的辅助方法。这些方法可显示约三分之二与发育异常相关的病变。

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