Chaambers M S, Jacob R J
Maxillofacial Prosthodontics/Dental Oncology, University of Texas M.D> Anderson Cancer Center, Houston, USA.
Tex Dent J. 1994 Jun;111(6):13-9.
Several concepts have been formed regarding the origin of primary malignancies, but only recently has a theory on second primary cancers evolved. The aim of this report is to review the literature regarding current concepts associated with carcinogenesis, tobacco and alcohol, oral premalignancy, field cancerization and cancer prevention.