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[淀粉样变性的分类]

[Classification of amyloidosis].

作者信息

Husby G

机构信息

Rikshospitalet, Oslo Sanitetsforenings Revmatismesykehus, Oslo.

出版信息

Tidsskr Nor Laegeforen. 1996 Jan 20;116(2):234-7.

PMID:8633331
Abstract

Amyloidosis is a collective term for a heterogeneous group of disorders characterized by deposition of a fibrillar, proteinaceous material, amyloid, in various tissues and organs. Increasing knowledge about the different proteins that constitute the amyloid fibrils has made it possible to classify amyloidosis by the fibril protein, which appears more rational than the traditional classification by its clinical symptoms. A group of experts on amyloidosis met in Oslo in 1990 and agreed upon a nomenclature and classification based on the chemical properties of the amyloid fibrils.

摘要

淀粉样变性是一组异质性疾病的统称,其特征是一种纤维状蛋白质物质——淀粉样蛋白沉积于各种组织和器官中。随着对构成淀粉样纤维的不同蛋白质的认识不断增加,根据纤维蛋白对淀粉样变性进行分类成为可能,这似乎比传统的按临床症状分类更为合理。1990年,一组淀粉样变性专家在奥斯陆会面,商定了基于淀粉样纤维化学性质的命名法和分类方法。

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