Loraas A, Lote K, Samdal H H, Beiske K, Langholm R
Onkologisk avdeling Det Norske Radiumhospital, Oslo.
Tidsskr Nor Laegeforen. 1996 Jan 20;116(2):238-41.
Human T-cell lymphotropic virus type I is an oncogenic retrovirus, endemic in Southwestern Japan, the Caribbean, some parts of Africa and Central and South America. The virus is etiologically associated with adult T-cell leukemia/lymphoma and a myelopathy called tropical spastic paraparesis or HTLV-I associated myelopathy. Transmission of the virus is almost identical to that of HIV. The latency period before onset of clinical symptoms can last from a few years (tropical spastic paraparesis) up to several decades (adult T-cell leukemia/lymphoma). Four different clinicopathological subtypes of the T-cell neoplasia are known, and in this article we describe two patients with the subtype lymphoma.
人类嗜T细胞病毒I型是一种致癌逆转录病毒,在日本西南部、加勒比地区、非洲部分地区以及中美洲和南美洲流行。该病毒在病因上与成人T细胞白血病/淋巴瘤以及一种称为热带痉挛性截瘫或HTLV-I相关脊髓病的脊髓病有关。该病毒的传播方式与HIV几乎相同。临床症状出现前的潜伏期可从数年(热带痉挛性截瘫)到数十年(成人T细胞白血病/淋巴瘤)不等。已知T细胞肿瘤有四种不同的临床病理亚型,在本文中我们描述了两名患有淋巴瘤亚型的患者。