尿毒症及透析对细胞介导免疫的影响。
The effect of uremia and dialysis on cell-mediated immunity.
作者信息
Wojtulewicz-Kurkus J, Klepacka J, Skopińska E, Górski A, Nowaczyk M, Orłowski T
出版信息
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):997-1000.
PMID:86344
Abstract
Delayed-type hypersensitivity to PPD, two types T rosettes as well as lymphokine production were studied in patients with end-stage renal failure maintained on hemodialysis. A significant impairment of skin reactivity and the lowering of the number of T cells were found, while no definite changes of lymphokine production were detected. No conclusive data are obtained as to the role of hemodialysis in reversing of immunologic deficits noted in uremia.
摘要
对接受血液透析维持治疗的终末期肾衰竭患者，研究了其对结核菌素纯蛋白衍生物的迟发型超敏反应、两种T玫瑰花结以及淋巴因子产生情况。发现皮肤反应性显著受损且T细胞数量减少，而未检测到淋巴因子产生有明确变化。关于血液透析在逆转尿毒症中所观察到的免疫缺陷方面的作用，未获得确凿数据。
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