Giacchino F, Giachino G, Giraudo G, Boero R, Basolo B, Bancale E, Nigra M, Piccoli G B, Piccoli G
Arch Sci Med (Torino). 1982 Jan-Mar;139(1):19-22.
To evaluate cellular immunity in uremia, we studied 235 uremic patients (178 on regular hemodialysis and 57 on medical treatment). E-rosettes were significantly lower (p less than 0.01) in all patients. The active E-rosettes test was found less significant to study T lymphocyte markers. The kind of correlations made with primary disease, small molecule levels, rehabilitation, suggests that cell-mediated immunodeficiency in uremia is a premature phenomenon and scarcely influenced by adequate hemodialysis treatment.
为评估尿毒症患者的细胞免疫功能，我们研究了235例尿毒症患者（178例接受常规血液透析，57例接受内科治疗）。所有患者的E花环均显著降低（p<0.01）。发现活性E花环试验对研究T淋巴细胞标志物的意义较小。与原发疾病、小分子水平、康复情况的相关性表明，尿毒症中的细胞介导免疫缺陷是一种早熟现象，且几乎不受充分血液透析治疗的影响。
