Meyer M A
Biomedical Imaging Center, University of Tennessee Medical Center, Knoxville, USA.
J Neuroimaging. 1996 Apr;6(2):117-9. doi: 10.1111/jon199662117.
A dynamic positron emission tomography (PET) study of the head was performed over 1 hour after the intravenous bolus administration of 18F-fluorodeoxyglucose (18F-FDG) to a 18-year-old patient with the clinical diagnosis of brain death. This dynamic PET study was performed on the seventh day after a severe posttraumatic closed-head injury. No intracerebral uptake or retention of tracer was noted, consistent with a diffuse absence of brain metabolism. A small amount of tracer was noted to slowly rise over time within the sagittal sinus, indicating that visualization of sagittal sinuses on technetium 99m-diethylene-triaminepentaacetic acid planar images could provide a falsely negative scintigraphic evaluation for the presence of brain death. It is concluded that PET FDG imaging may be a useful technique in evaluating patients for brain death.
对一名临床诊断为脑死亡的18岁患者静脉推注18F-氟脱氧葡萄糖（18F-FDG）后1小时内进行了头部动态正电子发射断层扫描（PET）研究。这项动态PET研究在严重创伤性闭合性颅脑损伤后的第七天进行。未观察到脑内有示踪剂摄取或滞留，这与脑代谢普遍缺失一致。注意到矢状窦内有少量示踪剂随时间缓慢上升，这表明锝99m-二乙三胺五乙酸平面图像上矢状窦的显影可能会对脑死亡的存在提供假阴性的闪烁扫描评估。得出的结论是，PET FDG成像可能是评估脑死亡患者的一种有用技术。
