el-Shirbiny A M, Yeung H, Imbriaco M, Michaeli J, Macapinlac H, Larson S M
Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
J Nucl Med. 1997 Aug;38(8):1208-10.
Experience of scintigraphic detection of bone lesion and active bone marrow involvement of multiple myeloma, especially with sestamibi and FDG-PET scans is in evolution. We report a case of intense sestamibi uptake in bone marrow correlating with the extent of the disease, while FDG-PET scans showed activity only in areas of active disease progression associated with pain. Technetium-99m-sestamibi appears to indicate the extent of the disease, while [18F]FDG-PET scans show sites of active tumor proliferation and may be useful in directing local therapy such as radiation.
