Khan A, Gazzaniga A B
Department of Cardiothoracic Surgery, University of California, Irvine Medical Center, Orange County 92668, USA.
Cardiovasc Surg. 1996 Feb;4(1):43-9. doi: 10.1016/0967-2109(96)83782-3.
Extracorporeal membrane oxygenation (ECMO) was initially developed for respiratory failure. Its use, however, has evolved into an excellent method of preoperative and postoperative support in the treatment of infants and children with acquired and congenital heart disease. Along with ECMO, the left ventricular assist device (LVAD) and the intraaortic balloon pump (IABP) have also found a place in the management of paediatric patients with heart failure. This report documents 15 patients who were treated with one or a combination of these mechanical devices, either preoperatively or postoperatively. There is a 74% survival rate and the long-term outcome has been excellent in most cases. The use of heparin-coated devices and tight regulation of heparin has allowed the transfer of infants and children from standard cardiopulmonary bypass to assist devices in the operating room. Mechanical devices are an essential adjunct for the preoperative and postoperative treatment of infants and children with cardiac disease.
体外膜肺氧合（ECMO）最初是为治疗呼吸衰竭而开发的。然而，其应用已发展成为治疗患有先天性和后天性心脏病的婴幼儿术前和术后支持的一种极佳方法。与ECMO一起，左心室辅助装置（LVAD）和主动脉内球囊泵（IABP）在小儿心力衰竭的治疗中也占据了一席之地。本报告记录了15例接受这些机械装置中的一种或联合使用这些装置进行术前或术后治疗的患者。生存率为74%，大多数病例的长期预后良好。使用肝素涂层装置并严格控制肝素，使得婴幼儿在手术室中能够从标准体外循环转换为辅助装置。机械装置是患有心脏病的婴幼儿术前和术后治疗的重要辅助手段。
