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上颌骨原发性尤因肉瘤,一种罕见但可治愈的发病部位:两例新病例报告,经放疗和全身化疗成功治愈

Primary Ewing's sarcoma of the maxilla, a rare and curable localization: report of two new cases, successfully treated by radiotherapy and systemic chemotherapy.

作者信息

Fiorillo A, Tranfa F, Canale G, Fariello I, D'Amore R, De Chiara C, Vassallo P, Muto P, De Rosa G, Bonavolonta G

机构信息

Department of Pediatrics, Faculty of Medicine, University Federico II of Naples, Italy.

出版信息

Cancer Lett. 1996 Jun 5;103(2):177-82. doi: 10.1016/0304-3835(96)04210-3.

Abstract

Primary maxillary localization of Ewing's sarcoma is unusual. Involvement of facial bones is characterized by clinical and radiological features distinct from those commonly observed in other sites. Because of the above peculiarities a delay in diagnosis and thus in starting treatment is very probable in such cases. We report here two new cases of Ewing's sarcoma localized to facial bones, successfully treated by local high dosage radiotherapy and systemic chemotherapy. Our experience suggests that, especially for particular sites not suitable to radical surgery, radiation therapy can represent an effective tool to achieve local control of the tumor.

摘要

尤因肉瘤原发于上颌骨的情况并不常见。面部骨骼受累的临床和放射学特征与其他部位常见的特征不同。由于上述特点,此类病例很可能会出现诊断延迟,进而导致治疗开始延迟。我们在此报告两例局限于面部骨骼的尤因肉瘤新病例,通过局部高剂量放疗和全身化疗成功治愈。我们的经验表明,特别是对于不适合根治性手术的特定部位,放射治疗可以成为实现肿瘤局部控制的有效手段。

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