快速眼动睡眠剥夺对大鼠睡眠呼吸暂停的影响。

Effect of REM sleep deprivation on sleep apneas in rats.

作者信息

Carley D W, Trbovic S, Radulovacki M

机构信息

Department of Pharmacology, College of Medicine, University of Illinois at Chicago, Illinois 60612, USA.

出版信息

Exp Neurol. 1996 Feb;137(2):291-3. doi: 10.1006/exnr.1996.0027.

DOI:10.1006/exnr.1996.0027

PMID:8635543

Abstract

We studied the effects of 48 h of REM sleep deprivation on spontaneous and post-sigh central apneas in Sprague-Dawley rates by simultaneously monitoring sleep by the EEG and respiration for 6 h. During the recovery sleep following REM deprivation a decrease in post-sigh apneas occurred in total sleep. There was no change in spontaneous apneas. The results suggest the existence of partially distinct mechanisms for the two types of apneas.

摘要

我们通过脑电图和呼吸监测6小时，研究了48小时快速眼动睡眠剥夺对斯普拉格-道利大鼠自发性和叹气后中枢性呼吸暂停的影响。在快速眼动睡眠剥夺后的恢复睡眠期间，总睡眠中叹气后呼吸暂停减少。自发性呼吸暂停没有变化。结果表明两种类型的呼吸暂停存在部分不同的机制。