Lau J Y, Chung S C, Sung J J, Chan A C, Ng E K, Suen R C, Li A K
Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong.
Gastrointest Endosc. 1996 Feb;43(2 Pt 1):98-101. doi: 10.1016/s0016-5107(06)80107-0.
Through-the-scope balloon dilation has been used for treatment of benign pyloric stenosis; however, long-term results are lacking in the literature.
A retrospective analysis using the Kaplan-Meier method.
Between November 1986 and December 1993, 54 patients underwent through-the-scope balloon dilations for pyloric stenosis. The mean age was 57.5 years. There were 5 (9.3%) initial treatment failures due to tight stenoses and perforations from dilation occurred in 4(7.4%) patients. Forty-five (83.3%) patients underwent successful dilation. Four patients developed rapid restenoses and were found to have malignant obstructions. Forty-one patients entered our study. Time at risk commenced on the date of initial dilation. The end point was defined at the time at which patients presented with recurrent obstruction or other ulcer complications. The median follow-up period was 39 months. The ulcer complication-free probability at 3 months, and at 1, 2, and 3 years was 79.1%, 73.4%, 69.3%, and 54.7%, respectively. In all, 21 (51.2%) patients required subsequent surgery: 18 for recurrent obstructions, 2 for interval perforations, and 1 for bleeding.
While through-the-scope balloon dilation may palliate symptoms of obstruction, recurrent obstruction and other ulcer complications are common. It should be reserved only for patients at high risk for operative surgery.
经内镜球囊扩张术已用于治疗良性幽门狭窄;然而,文献中缺乏长期结果。
采用Kaplan-Meier法进行回顾性分析。
1986年11月至1993年12月期间,54例患者接受了经内镜球囊扩张术治疗幽门狭窄。平均年龄为57.5岁。5例(9.3%)因狭窄严重导致初始治疗失败,4例(7.4%)患者在扩张时发生穿孔。45例(83.3%)患者扩张成功。4例患者出现快速再狭窄,经检查发现为恶性梗阻。41例患者进入我们的研究。风险期从首次扩张之日开始。终点定义为患者出现复发性梗阻或其他溃疡并发症的时间。中位随访期为39个月。3个月、1年、2年和3年时无溃疡并发症的概率分别为79.1%、73.4%、69.3%和54.7%。共有21例(51.2%)患者需要后续手术:18例因复发性梗阻,2例因间歇性穿孔,1例因出血。
虽然经内镜球囊扩张术可能缓解梗阻症状,但复发性梗阻和其他溃疡并发症很常见。它仅应保留用于手术风险高的患者。