Wittenberg J, Powell W M, Dinsmore R E, Miller S W, Maturi R A
Invest Radiol. 1977 May-Jun;12(3):215-23. doi: 10.1097/00004424-197705000-00003.
The capacity of computerized tomography to assess myocardial edema resulting from acute coronary occlusion was investigated in 19 arrested and 2 beating canine hearts. Edematous myocardium was consistently detected as areas of decreased attenuation values. The magnitude of the decrease in attenuation value was linearly related to the severity of the edema. The anatomic definition and tomographic information in the arrested hearts provided the capability for localization and quantitation of the extent of the lesion. The results of these in vitro investigations indicate that CT scanning is a technique which will contribute important pathophysiologic information about the evolution of myocardial ischemia.
在19只停跳和2只跳动的犬心脏中，研究了计算机断层扫描评估急性冠状动脉闭塞所致心肌水肿的能力。水肿心肌始终被检测为衰减值降低的区域。衰减值降低的幅度与水肿的严重程度呈线性相关。停跳心脏中的解剖学定义和断层扫描信息提供了定位和定量病变范围的能力。这些体外研究结果表明，CT扫描是一种将有助于提供有关心肌缺血演变的重要病理生理信息的技术。
