环孢素成功治疗系统性幼年型类风湿关节炎中的巨噬细胞活化综合征。
Macrophage activation syndrome in systemic juvenile rheumatoid arthritis successfully treated with cyclosporine.
作者信息
Ravelli A, De Benedetti F, Viola S, Martini A
机构信息
Clinica Pediatrica, Università di Pavia, Istituto di Ricovero e Cura a Carattere Scientifico S. Matteo, Italy.
出版信息
J Pediatr. 1996 Feb;128(2):275-8. doi: 10.1016/s0022-3476(96)70408-0.
PMID:8636829
Abstract
A macrophage activation syndrome, possibly related to methotrexate toxicity, developed in a boy with systemic juvenile rheumatoid arthritis. Corticosteroid administration was ineffective, whereas a prompt response to cyclosporine was observed. Two months later, Pneumocystis carinii pneumonia developed.
摘要
一名患有全身型幼年类风湿关节炎的男孩出现了可能与甲氨蝶呤毒性相关的巨噬细胞活化综合征。给予皮质类固醇治疗无效，而对环孢素观察到迅速反应。两个月后，发生了卡氏肺孢子虫肺炎。
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