Weathers W W, Snyder G K
J Appl Physiol Respir Environ Exerc Physiol. 1977 May;42(5):679-81. doi: 10.1152/jappl.1977.42.5.679.
Mouse deer possess the smallest known erythrocytes. In contrast to the usual biconcave shape, mouse deer corpuscles are spherical which results in an appreciable increase in vitro blood viscosity. In the absence of compensation, increased viscosity should produce hemodynamic consequences. However, we find that cardiac output, arterial pressure, and total peripheral resistance are all within normal limits, while packed cell volume is considerably lower than normal. We suggest that reduced packed cell volume represents a compensation for the spherical shape of the corpuscles, serving to maintain blood viscosity and dependent hemodynamic parameters within normal limits. These results contrast markedly with the pattern observed in man where conditions which result in a high in vitro blood viscosity also have significant hemodynamic consequences. Mean values for three mouse deer were: body mass, 1.18 kg; packed cell volume, 29.8%; heart rate, 182 beats/min; cardiac output, 145 ml-(kg-min)-1., mean arterial pressure, 99 Torr; total peripheral resistance, 4.90 X 10(5) dyn-s-cm-5.
鼷鹿拥有已知最小的红细胞。与通常的双凹形不同，鼷鹿的红细胞呈球形，这导致体外血液粘度显著增加。在没有代偿的情况下，粘度增加会产生血流动力学后果。然而，我们发现心输出量、动脉血压和总外周阻力均在正常范围内，而血细胞比容则明显低于正常水平。我们认为血细胞比容降低是对红细胞球形形状的一种代偿，有助于将血液粘度和相关血流动力学参数维持在正常范围内。这些结果与在人类中观察到的模式形成显著对比，在人类中，导致体外血液粘度升高的情况也会产生显著的血流动力学后果。三只鼷鹿的平均值为：体重1.18千克；血细胞比容29.8%；心率182次/分钟；心输出量145毫升·（千克·分钟）-1；平均动脉压99托；总外周阻力4.90×10(5)达因·秒·厘米-5 。
