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评估清醒犬振动诱发心血管反应的参数。

Parameters for assessing vibration-induced cardiovascular responses in awake dogs.

作者信息

Bhattacharya A, Knapp C F, McCutcheon E P, Edwards R G

出版信息

J Appl Physiol Respir Environ Exerc Physiol. 1977 May;42(5):682-9. doi: 10.1152/jappl.1977.42.5.682.

DOI:10.1152/jappl.1977.42.5.682
PMID:863832
Abstract

The vibration parameters for assessing the response of the cardiovascular system to whole-body vibration were studied. Six awake, chronically instrumented canines were restrained with their spines vertical, and exposed to GZ sinusoidal vibration of 2-12 HZ for a constant peak acceleration amplitude of +-1.0 G. Vibration exposures of 30 s with intervening recovery periods of 2 min were employed. The following variables were measured: mean heart rate (MHR), stroke volume (SV), mean aortic flow (MAF), mean aortic pressure (MAP), the peak net force transmitted to the canine/body weight (PNF/BW), and the vibration platform frequency (ft), displacement, and acceleration. The percentage change from control (no vibration) of MAF varied linearly with PNF/BW for all cases. MAF also varied linearly with the log MHR/ft for the number of dogs which primarily changed MHR during the vibration exposures. The response of MAP was minimal in all cases, indicating a decrease in total peripheral resistance with increasing PHF.

摘要

研究了用于评估心血管系统对全身振动反应的振动参数。六只清醒、长期植入仪器的犬被固定,使其脊柱垂直,并暴露于2 - 12赫兹的GZ正弦振动中,峰值加速度幅度恒定为±1.0G。采用30秒的振动暴露,中间间隔2分钟的恢复时间。测量了以下变量:平均心率(MHR)、每搏输出量(SV)、平均主动脉血流量(MAF)、平均主动脉压(MAP)、传递到犬体/体重的峰值净力(PNF/BW)以及振动平台频率(ft)、位移和加速度。在所有情况下,MAF相对于对照(无振动)的百分比变化与PNF/BW呈线性变化。对于在振动暴露期间主要改变MHR的犬只数量,MAF也与log MHR/ft呈线性变化。在所有情况下,MAP的反应最小,表明随着PHF增加,总外周阻力降低。

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Parameters for assessing vibration-induced cardiovascular responses in awake dogs.评估清醒犬振动诱发心血管反应的参数。
J Appl Physiol Respir Environ Exerc Physiol. 1977 May;42(5):682-9. doi: 10.1152/jappl.1977.42.5.682.
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