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骆驼的葡萄糖负荷与脱水

Glucose loading and dehydration in the camel.

作者信息

Yagil R, Berlyne G M

出版信息

J Appl Physiol Respir Environ Exerc Physiol. 1977 May;42(5):690-3. doi: 10.1152/jappl.1977.42.5.690.

Abstract

Five female bedouin camels were subjected to large infusions of glucose, both when water was readily available and following 10 days of water deprivation. When the camels were hydrated the extra glucose was readily given off in the urine with only a slight increase in blood levels. Following dehydration, the blood glucose levels increased greatly while the urinary excretion was limited. Dehydration led to decreased blood insulin levels, while glucose infusion led to increased levels. The data show that the acclimatization of the camel to dehydration is not only a question of long-term adaption to desert conditions but that even following acute nonphysiological stress, i.e., glucosuria, excess loss of body water was prevented.

摘要

五只雌性贝都因骆驼分别在随时可获取水时以及缺水10天后接受了大量葡萄糖输注。当骆驼处于水合状态时,额外的葡萄糖很容易通过尿液排出,血液水平仅略有升高。脱水后,血糖水平大幅升高,而尿液排泄受限。脱水导致血液胰岛素水平下降,而葡萄糖输注则导致胰岛素水平升高。数据表明,骆驼对脱水的适应不仅是长期适应沙漠环境的问题,而且即使在急性非生理性应激(即糖尿)后,也能防止身体水分过度流失。

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