Aus G, Bergdahl S, Frösing R, Lodding P, Pileblad E, Hugosson J
Department of Urology, Göteborg University, Ostra Hospital, Sweden.
Urology. 1996 Apr;47(4):529-31. doi: 10.1016/S0090-4295(99)80489-0.
The aim of the present study was to investigate how transurethral resection of the prostate (TURP) affected the serum levels of prostate-specific antigen (PSA) and to establish reference ranges of PSA in patients who have undergone TURP.
PSA was determined preoperatively and 3 months postoperatively in 190 patients who underwent TURP because of benign prostatic hyperplasia (BPH).
Mean PSA levels were reduced by 70%, from 6.0 to 1.9 ng/mL. Prostate volume was reduced by 58% from 63.3 to 26.5 cc, which is close to the reported normal volume in men without BPH. Ninety percent of the patients had a postoperative PSA value of less than 4 ng/mL and 98% less than 10 ng/mL.
After a complete TURP with a benign histopathologic specimen, PSA should be expected to be within the normal reference range, that is, less than 4 ng/mL.
本研究旨在探讨经尿道前列腺电切术（TURP）如何影响前列腺特异性抗原（PSA）的血清水平，并建立接受TURP患者的PSA参考范围。
对190例因良性前列腺增生（BPH）接受TURP的患者在术前和术后3个月测定PSA。
PSA平均水平降低了70%，从6.0降至1.9 ng/mL。前列腺体积从63.3 cc降至26.5 cc，减少了58%，这接近报道的无BPH男性的正常体积。90%的患者术后PSA值小于4 ng/mL，98%小于10 ng/mL。
在获得良性组织病理学标本的完整TURP术后，PSA应预期在正常参考范围内，即小于4 ng/mL。
