[甲胎蛋白在体外抑制角质形成细胞增殖]
[Alpha-fetoprotein suppresses keratinocyte proliferation in vitro].
作者信息
Voroteliak E A, Vasil'ev A V, Gusev S A, Povaliĭ T M, Terskikh V V
出版信息
Izv Akad Nauk Ser Biol. 1996 Jan-Feb(1):117-20.
PMID:8640109
Abstract
The influence of alpha-fetoprotein (AFP) on the proliferation of human epidermal keratinocytes in vitro has been studied. AFP (1p microgram/ ml) inhibits the proliferation of keratinocytes cultivated in a serum-free medium. The addition of fetal bovine serum significantly enhances the effect of AFP in this culture. A similar effect of AFP is observed in a medium with a low content of calcium ions.
摘要
已经研究了甲胎蛋白（AFP）对体外培养的人表皮角质形成细胞增殖的影响。AFP（1微克/毫升）抑制在无血清培养基中培养的角质形成细胞的增殖。添加胎牛血清可显著增强AFP在这种培养体系中的作用。在钙离子含量低的培养基中也观察到了AFP的类似作用。
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