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Cisplatin and derived anticancer drugs: mechanism and current status of DNA binding.

作者信息

Bloemink M J, Reedijk J

机构信息

Leiden Institute of Chemistry, Gorlaeus Laboratories, Leiden University, The Netherlands.

出版信息

Met Ions Biol Syst. 1996;32:641-85.

PMID:8640534
Abstract
摘要

相似文献

1
Cisplatin and derived anticancer drugs: mechanism and current status of DNA binding.顺铂及衍生抗癌药物：DNA结合机制与现状
Met Ions Biol Syst. 1996;32:641-85.
2
Current status of structure-activity relationships of platinum anticancer drugs: activation of the trans geometry.
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3
Trans-diammineplatinum(II): what makes it different from cis-DDP? Coordination chemistry of a neglected relative of cisplatin and its interaction with nucleic acids.反式二氨合铂（II）：它与顺铂有何不同？顺铂一个被忽视的同类物的配位化学及其与核酸的相互作用。
Met Ions Biol Syst. 1996;33:105-41.
4
NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin.含有顺式二氨合铂（II）d（GpG）链内交联的DNA十二聚体双链体的核磁共振溶液结构，抗癌药物顺铂的主要加合物。
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6
Proteins that bind to and mediate the biological activity of platinum anticancer drug-DNA adducts.与铂类抗癌药物-DNA加合物结合并介导其生物活性的蛋白质。
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7
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A combined effect of molecular electrostatic potential and N7 accessibility explains sequence-dependent binding of cis-[Pt(NH3)2(H2O)2]2+ to DNA duplexes.
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DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines.含哌啶、哌嗪或4-甲基吡啶配体的新型抗肿瘤非经典铂配合物在无细胞培养基中顺式和反式几何构型的DNA结合模式。及其与癌细胞系活性的关系。
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Gadolinium texaphyrin (Gd-Tex)-malonato-platinum conjugates: synthesis and comparison with carboplatin in normal and Pt-resistant cell lines.钆四吡嗪（Gd-Tex）-丙二酸盐-铂缀合物：在正常和铂耐药细胞系中的合成及与卡铂的比较。
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In silico approach to cisplatin toxicity. Quantum chemical studies on platinum(II)-cysteine systems.顺铂毒性的计算机模拟方法。铂（II）-半胱氨酸体系的量子化学研究。
J Mol Model. 2009 Jun;15(6):659-64. doi: 10.1007/s00894-009-0469-2. Epub 2009 Feb 17.
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Rearrangement of a 1,3-trans-[Pt(NH3)2[(GXG)-N7G,N7G]] intrastrand cross-link into interstrand cross-links within RNA duplexes.1,3-反式-[铂(氨)₂[(GXG)-N7G,N7G]]链内交联在RNA双链体中重排为链间交联。
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Development and application of a simple assay to quantify cellular adducts of platinum complexes with DNA.一种用于定量铂配合物与DNA细胞加合物的简单检测方法的开发与应用。
Pharm Res. 1999 Mar;16(3):470-3. doi: 10.1023/a:1011950524701.