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Pyrazinamide--on the antituberculosis drug frontline.

作者信息

Mitchison D A

机构信息

Department of Medical Microbiology, St George's Hospital Medical School, London, UK.

出版信息

Nat Med. 1996 Jun;2(6):635-6. doi: 10.1038/nm0696-635.

DOI:10.1038/nm0696-635
PMID:8640549
Abstract
摘要

相似文献

1
Pyrazinamide--on the antituberculosis drug frontline.
Nat Med. 1996 Jun;2(6):635-6. doi: 10.1038/nm0696-635.
2
Pyrazinamide: a frontline drug used for tuberculosis. Molecular mechanism of action resolved after 50 years?吡嗪酰胺:一种用于治疗结核病的一线药物。50年后其作用分子机制得以阐明?
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Mutations found in the pncA gene of Mycobacterium tuberculosis in clinical pyrazinamide-resistant isolates from a local region of China.在中国某一地区临床耐吡嗪酰胺结核分枝杆菌分离株中发现的结核分枝杆菌pncA基因的突变。
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A simplified pyrazinamidase test for pyrazinamide drug susceptibility in Mycobacterium tuberculosis.一种用于检测结核分枝杆菌对吡嗪酰胺药物敏感性的简化吡嗪酰胺酶试验。
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Escherichia coli genes involved in resistance to pyrazinoic acid, the active component of the tuberculosis drug pyrazinamide.
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pncA Gene Mutations Associated with Pyrazinamide Resistance in Drug-Resistant Tuberculosis, South Africa and Georgia.南非和格鲁吉亚耐多药结核病中与吡嗪酰胺耐药相关的pncA基因突变
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Mechanistic analysis elucidating the relationship between Lys96 mutation in Mycobacterium tuberculosis pyrazinamidase enzyme and pyrazinamide susceptibility.阐明结核分枝杆菌吡嗪酰胺酶中Lys96突变与吡嗪酰胺敏感性之间关系的机制分析。
BMC Genomics. 2015;16 Suppl 2(Suppl 2):S14. doi: 10.1186/1471-2164-16-S2-S14. Epub 2015 Jan 21.

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Modulating the Global Response Regulator, LuxO of Quorum Sensing System Using a Pyrazine Dicarboxylic Acid Derivative (PDCA): An Antivirulence Approach.利用吡嗪二羧酸衍生物(PDCA)调节群体感应系统的全局响应调节剂 LuxO:一种抗毒力方法。
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2
A Computational Study of Cytotoxicity of Substituted Amides of Pyrazine- 2-carboxylic acids Using QSAR and DFT Based Molecular Surface Electrostatic Potential.基于QSAR和DFT的分子表面静电势对吡嗪-2-羧酸取代酰胺细胞毒性的计算研究
Iran J Pharm Res. 2013 Fall;12(4):745-50.
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Evaluation of standard chemotherapy in the guinea pig model of tuberculosis.
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