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[高血压与冠心病。通过控制体重实现全球风险适度降低]

[Hypertension and coronary heart disease. Global risk moderation through control of body weight].

作者信息

Suter P M, Häsler E, Vetter W

机构信息

Departement für Innere Medizin, Medizinische Poliklinik, Universitätsspital, Zürich.

出版信息

Praxis (Bern 1994). 1996 Jan 30;85(5):113-6.

PMID:8643904
Abstract

The moderation control of blood pressure is one key strategy to control the progression of coronary artery disease. In the pathogenesis of coronary artery disease, hypertension should not be viewed on its own; however, other risk factors, which may influence hypertension and atherogenesis at the same time, should be evaluated carefully. In primary and also secondary prevention of coronary artery disease, overweight and obesity play an important modulating role. Especially the abdominal (visceral) form of obesity should be controlled. The reduction of dietary fat intake seems to be the major strategy to control body fat accumulation and weight gain, since the intake of excess fat does not lead to an increased oxidation of fat. The reduction of fat intake is also the major nonpharmacological strategy to promote regression of atherosclerosis and to control body weight.

摘要

血压的适度控制是控制冠状动脉疾病进展的一项关键策略。在冠状动脉疾病的发病机制中,不应孤立地看待高血压;然而,对于可能同时影响高血压和动脉粥样硬化形成的其他危险因素,应仔细评估。在冠状动脉疾病的一级和二级预防中,超重和肥胖起着重要的调节作用。尤其应控制腹部(内脏)型肥胖。减少膳食脂肪摄入似乎是控制体脂堆积和体重增加的主要策略,因为过量脂肪摄入并不会导致脂肪氧化增加。减少脂肪摄入也是促进动脉粥样硬化消退和控制体重的主要非药物策略。

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