van Houten J P, Rothman A, Bejar R
Department of Pediatrics, University of California San Diego Medical Center, 92103, USA.
Am J Perinatol. 1996 Jan;13(1):47-53. doi: 10.1055/s-2007-994202.
The objective of this retrospective study was to determine the incidence and types of cranial ultrasound abnormalities in full-term infants with congenital heart disease (CHD). We reviewed the cranial ultrasound scans of 49 full-term infants with CHD and compared them to 42 healthy full-term control infants. The relationship of each abnormality with the type of CHD, the presence of cyanosis, and cardiac catheterization and cardiac surgery were examined. We found that infants with CHD had a higher incidence of cranial ultrasound abnormalities than control infants (59% versus 14%; p < 0.001). Cerebral atrophy and linear echodensities in the basal ganglia and thalamus were the most common sonographic findings in infants with CHD, particularly in those with coarctation of the aorta or ventricular septal defect. Intraventricular hemorrhage occurred more often in infants with acryanotic CHD than in those with cyanotic CHD. Cardiac catheterization and cardiac surgery had no significant effects on cranial ultrasound findings. We conclude that cranial ultrasound abnormalities are very frequent in full-term infants with CHD. These findings emphasize the importance of cranial ultrasonography and long-term neurodevelopmental follow-up of infants with CHD.
这项回顾性研究的目的是确定患有先天性心脏病（CHD）的足月儿颅内超声异常的发生率和类型。我们回顾了49例患有CHD的足月儿的颅内超声扫描结果，并将其与42例健康足月儿对照婴儿进行比较。研究了每种异常与CHD类型、青紫的存在、心导管检查及心脏手术之间的关系。我们发现，患有CHD的婴儿颅内超声异常的发生率高于对照婴儿（59%对14%；p<0.001）。脑萎缩以及基底节和丘脑的线状高回声是患有CHD婴儿最常见的超声表现，尤其是在患有主动脉缩窄或室间隔缺损的婴儿中。无青紫型CHD婴儿的脑室内出血比青紫型CHD婴儿更常见。心导管检查和心脏手术对颅内超声检查结果无显著影响。我们得出结论，患有CHD的足月儿颅内超声异常非常常见。这些发现强调了颅内超声检查以及对患有CHD婴儿进行长期神经发育随访的重要性。
