[人类白细胞抗原与耳硬化症]

[Human leukocyte antigen and otosclerosis].

作者信息

Gamir M A, Mallea I, Marco J, Rubio F, Orts M

机构信息

Servicio de ORL, Hospital Clínico Universitario, Valencia.

出版信息

Acta Otorrinolaringol Esp. 1996 Jan-Feb;47(1):26-8.

PMID:8645485

Abstract

Fifty patients (32 women, 18 men) who underwent stapedectomy [FISCH, V. (1), 1982] for otosclerosis were studied. Histo-compatibility antigens were typed in all patients using the microlymphocytic test to determine antigens of the HLA system loci A and B. Statistical comparison of results with those obtained in a control group of 339 persons without otosclerosis showed that otosclerosis has a genetic HLA-related component.

摘要

对50例（32名女性，18名男性）因耳硬化症接受镫骨切除术的患者[菲施，V.（1），1982年]进行了研究。使用微量淋巴细胞试验对所有患者进行组织相容性抗原分型，以确定HLA系统位点A和B的抗原。将结果与339名无耳硬化症的对照组人员的结果进行统计学比较，结果表明耳硬化症具有与HLA相关的遗传成分。