Mengozzi G, Veglio F, Schiavone D, Inconis T, Mulatero P, Paradisi L
Dipartimento di Medicina e Oncologia Sperimentale, Università degli Studi di Torino.
Ann Ital Med Int. 1996 Jan-Mar;11(1):46-51.
The L-arginine/nitric oxide (NO) pathway plays a key role in a number of biological processes within most organs and systems. Increasing attention has been addressed to its involvement in the pathogenesis of various human diseases. In this review we examine the enzymology of different NO-synthase isoforms, the major NO detection techniques as well as the possible clinical and pharmacological implications of this new metabolic pathway.
L-精氨酸/一氧化氮（NO）途径在大多数器官和系统的许多生物过程中起着关键作用。人们越来越关注其在各种人类疾病发病机制中的作用。在这篇综述中，我们研究了不同一氧化氮合酶同工型的酶学、主要的NO检测技术以及这条新代谢途径可能的临床和药理学意义。
