Schwartz B L, Rosse R B, Veazey C, Deutsch S I
Department of Veterans Affairs Medical Center, Psychiatry Service (116A), Washington, DC 20422, USA.
Biol Psychiatry. 1996 Feb 15;39(4):241-8. doi: 10.1016/0006-3223(95)00130-1.
We assessed skill learning in young and older schizophrenic patients using the rotary pursuit task. Schizophrenic patients displayed impaired learning on this task compared with normal control subjects, but older patients were not more impaired than young ones. The patients' rotary pursuit learning was not correlated to the severity of abnormal movements or to their treatment with medication, but it was associated to conceptual abilities assessed on the Dementia Rating Scale (Mattis 1988). An impairment in acquiring motor procedures in this task might reflect neuropsychological deficits associated with corticostriatal pathology.
我们使用旋转追踪任务评估了年轻和老年精神分裂症患者的技能学习情况。与正常对照受试者相比，精神分裂症患者在该任务上的学习表现受损，但老年患者的受损程度并不比年轻患者更严重。患者的旋转追踪学习与异常运动的严重程度或药物治疗无关，但与在痴呆评定量表（马蒂斯，1988年）上评估的概念能力相关。在该任务中获取运动程序的受损可能反映了与皮质纹状体病变相关的神经心理学缺陷。
