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免疫功能正常成年人的汉赛巴尔通体心内膜炎

Bartonella henselae endocarditis in an immunocompetent adult.

作者信息

Holmes A H, Greenough T C, Balady G J, Regnery R L, Anderson B E, O'Keane J C, Fonger J D, McCrone E L

机构信息

Department of Medicine, Boston University School of Medicine, Boston University Medical Center Hospital, Massachusetts, USA.

出版信息

Clin Infect Dis. 1995 Oct;21(4):1004-7. doi: 10.1093/clinids/21.4.1004.

DOI:10.1093/clinids/21.4.1004
PMID:8645787
Abstract

We describe a case of aggressive Bartonella henselae endocarditis in an immunocompetent man who owned a cat. Aortic valve replacement was required, and his infection was diagnosed by histology, serology, and polymerase chain reaction analysis. The manifestations of his disease included mediastinal lymphadenopathy, glomerulonephritis, myocarditis, and a petechial rash; the unusual finding of a positive titer of c-antineutrophil cytoplasmic antibodies was noted. Serological titers were markedly elevated for > 1 year despite clinical improvement.

摘要

我们描述了一例在一名免疫功能正常且养猫的男性中发生的侵袭性汉赛巴尔通体心内膜炎病例。患者需要进行主动脉瓣置换,其感染通过组织学、血清学和聚合酶链反应分析得以诊断。他的疾病表现包括纵隔淋巴结肿大、肾小球肾炎、心肌炎和瘀点皮疹;还发现了抗中性粒细胞胞浆抗体滴度呈阳性这一不寻常的情况。尽管临床症状有所改善,但血清学滴度在一年多的时间里仍显著升高。

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Bartonella henselae endocarditis in an immunocompetent adult.免疫功能正常成年人的汉赛巴尔通体心内膜炎
Clin Infect Dis. 1995 Oct;21(4):1004-7. doi: 10.1093/clinids/21.4.1004.
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