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与主动脉瘤相关的术前弥散性血管内凝血(DIC)——手术前需要纠正吗?

Preoperative disseminated intravascular coagulation (DIC) associated with aortic aneurysm--does it need to be corrected before surgery?

作者信息

Oba J, Shiiya N, Matsui Y, Goda T, Sakuma M, Yasuda K

机构信息

Department of Cardiovascular Surgery, Hokkaido University School of Medicine, Sapporo, Japan.

出版信息

Surg Today. 1995;25(12):1011-4. doi: 10.1007/BF00311684.

DOI:10.1007/BF00311684
PMID:8645932
Abstract

Disseminated intravascular coagulation (DIC) is one of the complications accompanying aortic aneurysm. We herein report four patients with aortic aneurysm who had DIC preoperatively. In all four cases, DIC was corrected immediately after surgery; however, in two cases, DIC could not be corrected preoperatively. This prompted us to reconsider the importance of correcting DIC before surgery. Of the four cases reported in this paper, DIC existed even at the time of surgery in two cases, in spite of meticulous treatment with heparin and/or protease inhibitor; however, the DIC could be removed postoperatively even in these two cases. Surgeons should not waste time with intensive DIC treatment preoperatively. If the DIC cannot be corrected within more than 2 weeks of meticulous treatment, surgeons should then perform surgery on the patient. In addition, it is also essential to ensure that the DIC is due to the aneurysm itself and that no other disease processes have been overlooked.

摘要

弥散性血管内凝血(DIC)是主动脉瘤的并发症之一。我们在此报告4例术前发生DIC的主动脉瘤患者。在所有4例患者中,DIC在术后立即得到纠正;然而,有2例患者术前未能纠正DIC。这促使我们重新考虑术前纠正DIC的重要性。在本文报告的4例病例中,尽管用肝素和/或蛋白酶抑制剂进行了精心治疗,但仍有2例患者在手术时仍存在DIC;然而,即使在这2例患者中,DIC在术后也得以消除。外科医生不应在术前对DIC进行强化治疗上浪费时间。如果经过2周以上的精心治疗DIC仍无法纠正,外科医生应 then 对患者进行手术。此外,确保DIC是由动脉瘤本身引起且没有忽视其他疾病过程也至关重要。

注

原文中“then”在句中逻辑不清晰,推测可能有误,暂按原文翻译。

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