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脂质体:医学中的呈现及当前应用趋势

Liposomes: presentation and actual applicative trends in medicine.

作者信息

Bejan A, Turcu G

机构信息

Institute of Atomic Physics, IFIN, Măgurele-Bucharest, Romania.

出版信息

Rom J Intern Med. 1995 Jul-Dec;33(3-4):141-9.

PMID:8646185
Abstract

In this paper the main aspects of characterization, handling and applications of liposomes are presented. In the last 25 years much attention has been focused to liposomal systems for optimization of the drug targeting. Several pathways to optimize the drug action of liposomes in various situations as cancer, microbial therapy, vaccines, oral therapy and diagnosis were tested. Certain applications of liposomes especially those implying the phagocytic cells sustain a real interest for industrial applications.

摘要

本文介绍了脂质体的表征、处理及应用的主要方面。在过去25年里,脂质体系统在优化药物靶向方面备受关注。人们测试了多种途径来优化脂质体在癌症、微生物治疗、疫苗、口服治疗及诊断等各种情况下的药物作用。脂质体的某些应用,尤其是那些涉及吞噬细胞的应用,对工业应用具有实际意义。

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