Hewertson J, Boyd S G, Samuels M P, Neville B G, Southall D P
Academic Department of Paediatrics, University of Keele, North Staffordshire Hospital, Stoke-on-Trent, UK.
Dev Med Child Neurol. 1996 Jun;38(6):511-22. doi: 10.1111/j.1469-8749.1996.tb12112.x.
In order to measure epileptic seizure(ES)-induced hypoxaemia and explore its relation to other physiological changes, 53 seizures were documented in 10 children (aged 1 week to 5 years) during continuous recordings of breathing, ECG, oxygenation and EEG. Hypoxaemia was demonstrated in 42 ESs with an arterial oxygen saturation (SaO2) below baseline for a median duration of 100s and < or = 60% for 17s, despite resuscitation. There were pauses in breathing movements in 45 seizures, but only 35 of these were hypoxaemic; pauses of comparable severity occurred in the 10 seizures without hypoxaemia. In seven seizures there was hypoxaemia without pauses in breathing movements, although continued nasal airflow was not demonstrable. Sinus tachycardia occurred in 35 seizures and T-wave changes in 20, but no sinister arrhythmias were observed.
为了测量癫痫发作（ES）诱发的低氧血症，并探究其与其他生理变化的关系，在对10名儿童（年龄从1周龄至5岁）进行呼吸、心电图、氧合及脑电图连续记录期间，记录到了53次癫痫发作。在42次癫痫发作中证实存在低氧血症，尽管进行了复苏，但动脉血氧饱和度（SaO2）低于基线水平，持续时间中位数为100秒，且有17秒低于或等于60%。45次癫痫发作中有呼吸运动暂停，但其中只有35次存在低氧血症；在无低氧血症的10次癫痫发作中出现了严重程度相当的呼吸暂停。在7次癫痫发作中，尽管未显示有持续的鼻腔气流，但存在无呼吸运动暂停的低氧血症。35次癫痫发作出现窦性心动过速，20次出现T波改变，但未观察到严重心律失常。
