夏威夷考艾岛日本裔夏威夷人中的角化棘皮瘤。
Keratoacanthoma in Japanese Hawaiians in Kauai, Hawaii.
作者信息
Reizner G T, Chuang T Y, Elpern D J, Stone J L, Farmer E R
机构信息
Department of Medicine, University of Wisconsin School of Medicine, Madison, USA.
出版信息
Int J Dermatol. 1995 Dec;34(12):851-3. doi: 10.1111/j.1365-4362.1995.tb04420.x.
BACKGROUND
This is the first incidence report of keratoacanthoma (KA) in a Japanese ethnic population.
METHODS
The study was designed as a 5-year prospective incidence study using an island-wide survey of Japanese residents in Kauai, Hawaii, during the years 1983 through 1987.
RESULTS
Eleven Japanese residents of Kauai, three men and eight women, had KA. The crude incidence is 22.1 per 100,000 Japanese Kauaiian population. Two thirds of the lesions were on the extremities. No recurrence was noted, but a nonmelanoma skin cancer developed in some patients.
CONCLUSIONS
The incidence of KA in a Japanese ethnic population is not low. Ultraviolet light exposure must, in part, contribute to the development of KA. This is supported by fact that the incidence of KA in Japanese residents in Kauai is much higher than in Japan and that most of the KAS appear on exposed skin.
背景
这是日本裔人群中首例角化棘皮瘤（KA）发病率报告。
方法
本研究设计为一项为期5年的前瞻性发病率研究，于1983年至1987年期间对夏威夷考艾岛的日本居民进行全岛范围调查。
结果
考艾岛的11名日本居民患有KA，其中3名男性，8名女性。粗发病率为每10万日本考艾岛居民22.1例。三分之二的病损位于四肢。未观察到复发情况，但部分患者发生了非黑色素瘤皮肤癌。
结论
日本裔人群中KA的发病率不低。紫外线暴露在一定程度上必定促成了KA的发生。考艾岛日本居民中KA的发病率远高于日本，且大多数KA出现在暴露皮肤上，这一事实支持了这一观点。
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