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脑血管意外患者血脂谱及心肌酶变化的评估

Evaluation of serum lipid profile and cardiac enzyme changes in cerebrovascular accidents.

作者信息

Aggarwal S P, Thukral R, Wander G S, Kapoor D K

机构信息

Department of Medicine, Dayanand Medical College and Hospital, Ludhiana.

出版信息

J Indian Med Assoc. 1995 Sep;93(9):331-2.

PMID:8648151
Abstract

Serum lipid profile is, total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL) and triglycerides and serum cardiac enzymes ie, creatinine phosphokinase (CPK), creatinine phosphokinase isoenzyme MB (CPK-MB), lactate dehydrogenase (LDH) and serum aspartate aminotransferase (AST/SGOT) levels were estimated in 50 cases of cerebrovascular accidents (CVA) consisting of 26 cases of cerebral haemorrhage and 24 cases of cerebral thrombosis. All analyses were made on day 1 and day 7. Serum cholesterol, LDL and triglycerides levels were significantly higher in CVA patients on day 1. Lipid level fell significantly on day 7 in respect to day 1. On comparing the lipid levels between cerebral haemorrhage and cerebral thrombosis, no significant difference was observed. Cardiac enzymes like CPK and CPK-MB were significantly raised whereas, AST/SGOT and LDH were marginally raised on day 1 in CVA patients. However, there was no change in cardiac enzyme levels between cerebral haemorrhage and cerebral thrombosis patients.

摘要

对50例脑血管意外(CVA)患者进行了血清脂质谱分析,包括总胆固醇、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)和甘油三酯,以及血清心肌酶,即肌酸磷酸激酶(CPK)、肌酸磷酸激酶同工酶MB(CPK-MB)、乳酸脱氢酶(LDH)和血清天冬氨酸转氨酶(AST/SGOT)水平。其中脑出血26例,脑血栓形成24例。所有分析均在第1天和第7天进行。CVA患者第1天的血清胆固醇、LDL和甘油三酯水平显著升高。与第1天相比,第7天血脂水平显著下降。比较脑出血和脑血栓形成患者的血脂水平,未观察到显著差异。CVA患者第1天心肌酶如CPK和CPK-MB显著升高,而AST/SGOT和LDH略有升高。然而,脑出血和脑血栓形成患者之间心肌酶水平没有变化。

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