Dadić D, Alfirević I, Stefancić L, Nikić N, Baudoin Z, Ivancan V, Anić D, Bulat C, Jelić I
Klinika za kirurgiju Medicinskog bolnickog centra Rebro, Zagreb.
Lijec Vjesn. 1995 Jun;117 Suppl 2:78-80.
In this study we have evaluated 32 patients who underwent open heart surgery with extracorporeal circulation. The aim of the study was to determine the influence of duration of surgical procedure, amount of bleeding after surgery, duration of assisted ventilation, need for mechanical and pharmacological assistance on the occurrence of complications in the early postoperative period. Sixteen patients who developed signs of systemic infection were evaluated. Other 16 patients had similar clinical characteristics and they were operated on the same day or within the same week as patients in the first group and they served as the controls. There was a statistically significant difference between those two groups in the duration of surgical procedure, amount of blood loss after surgery, amount of transfusions and duration of mechanical ventilation. The group of patients with systemic infection and other complications required in the majority cases left ventricular support and developed multiorgan system failure that resulted in a higher rate of mortality. In conclusion, this study shows that the causes of complications and systemic infection in the early postoperative period could be due to a greater blood loss following surgery, demand for blood transfusions and duration of mechanical ventilation.
在本研究中，我们评估了32例行体外循环心脏直视手术的患者。本研究的目的是确定手术时间、术后出血量、辅助通气时间、机械和药物辅助需求对术后早期并发症发生情况的影响。对16例出现全身感染迹象的患者进行了评估。另外16例患者具有相似的临床特征，他们与第一组患者在同一天或同一周内接受手术，并作为对照组。两组在手术时间、术后失血量、输血量和机械通气时间方面存在统计学上的显著差异。发生全身感染和其他并发症的患者组在大多数情况下需要左心室支持，并出现多器官系统衰竭，导致死亡率较高。总之，本研究表明，术后早期并发症和全身感染的原因可能是术后出血量增加、输血需求和机械通气时间延长。
