Martín Rubí J C, Yélamos Rodríguez F, Laynez Bretones F, Córdoba Escámez J, Díez García F, Lardelli Claret A, Blanco Coronado J L, Vicente Rull J R
Unidad de Medicina Intensiva, Hospital Torrecárdenas, Almería.
Rev Clin Esp. 1996 Mar;196(3):145-9.
A total of 506 cases of acute poisoning with organophosphorus insecticides attended at Hospital Torrecárdenas, Almería, from 1981 to 1992 were prospectively studied. In all cases a predetermined clinical and therapeutical protocol was followed. Eighty per cent of poisoning events were accidental in nature, most occurred in males, greenhouse workers, and the toxic agents was most commonly absorbed through the skin and airways. All patients presented initially with overt cholinergic symptoms. The presence of bronchorrhea, tremor-fasciculations, respiratory depression and a lower level of consciousness was associated with severe poisonings. Uncommon and exceptional complications included: 5 cases with complete atrio-ventricular block, 3 cases with pancreatitis, 17 cases with endogenous re-intoxications and 3 patients with central diabetes insipidus.
对1981年至1992年期间在阿尔梅里亚省托雷卡德纳斯医院就诊的506例有机磷杀虫剂急性中毒病例进行了前瞻性研究。所有病例均遵循预先确定的临床和治疗方案。80%的中毒事件为意外性质，大多数发生在男性、温室工人身上，毒物最常通过皮肤和呼吸道吸收。所有患者最初均表现出明显的胆碱能症状。出现支气管分泌过多、震颤 - 肌束震颤、呼吸抑制和意识水平降低与严重中毒有关。罕见和特殊的并发症包括：5例完全性房室传导阻滞、3例胰腺炎、17例内源性再中毒和3例中枢性尿崩症患者。
