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[心脏手术中的脑损伤]

[Cerebral insult in heart surgery].

作者信息

Egloff L, Laske A, Siebenmann R, Studer M, Keller H

机构信息

HerzZentrum Hirslanden, Zürich.

出版信息

Schweiz Med Wochenschr. 1996 Mar 23;126(12):477-82.

PMID:8650512
Abstract

The aim of the study was to identify causes for perioperative stroke in cardiac surgery in order to reduce its occurrence. From 1989 to 1994, 3593 open heart operations were performed in adult patients. In 59 patients carotid endarterectomy for high grade stenosis was combined with the cardiac operation. There were a total of 68 (2%) focal strokes, 41 of which were considered minor and 14 major; 13 were lethal. The etiology of the 27 major and lethal events was most probably an embolus from the ascending aorta (6), from the ascending aorta or a cardiac valve (5), a thrombus in the left heart (6), air (1), cardiac arrest and resuscitation (4), cerebral hemorrhage (1), preoperatively unknown but high grade internal carotid stenosis (3), and a 50% stenosis of both internal carotid arteries preoperatively known but not operated on (1). There were 2 minor but no major neurologic complications in patients undergoing a combined carotid and cardiac procedure. A wide indication for preoperative neuroangiologic examination, echocardiography and careful intraoperative management may help to identify sources of possible emboli. Endarterectomy of high grade carotid stenosis is recommended simultaneously with the cardiac procedure.

摘要

本研究的目的是确定心脏手术围手术期卒中的病因,以减少其发生。1989年至1994年,对成年患者进行了3593例心脏直视手术。其中59例患者因高度狭窄行颈动脉内膜切除术并同期进行心脏手术。共有68例(2%)局灶性卒中,其中41例为轻度,14例为重度;13例致死。27例重度和致死性事件的病因最可能是升主动脉栓子(6例)、升主动脉或心脏瓣膜栓子(5例)、左心血栓(6例)、空气栓子(1例)、心脏骤停及复苏(4例)、脑出血(1例)、术前未知但存在高度颈内动脉狭窄(3例)以及术前已知双侧颈内动脉狭窄50%但未手术治疗(1例)。接受颈动脉和心脏联合手术的患者有2例轻度神经并发症,但无重度神经并发症。术前广泛开展神经血管造影检查、超声心动图检查以及术中仔细管理,可能有助于识别潜在栓子来源。建议在心脏手术同期行高度颈动脉狭窄内膜切除术。

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