Barakat R, Farghaly A, el Masry A G, elSayed M K, Husein M H, Miller F D
High Institute of Public Health, Alexandria University, Egypt.
Trop Geogr Med. 1995;47(6):259-65.
This is an early descriptive report of the 'Epidemiology 123' project in Egypt which makes use of large probability sampling methods. These results focus on Schistosoma mansoni infection in the northern Nile Delta Governorate of Kafr El Sheikh. A probability sample of 18,777 persons, representing the rural population of the entire Governorate, was drawn. The sample was designed not to exclude villages based on location or presence of health care facilities and to include representation of the smaller ezbas or hamlets. The objective was to obtain detailed estimates on age and sex specific patterns of S. mansoni infection, and to provide a baseline for prospective studies. Stool specimens were examined by the Kato method. The estimated prevalence of S. monsoni infection in the rural population was 39.3% (SE +/- 3.3) in 44 villages and ezbas after weighing for the effects of the sample design. The estimated geometric mean egg count per gram stool (GMEC) was 72.9 (SE +/- 7.3). Prevalence and GMEC varied considerably by village and ezba, with ezbas having a significantly higher prevalence. Villages and ezba specific prevalence was strongly associated with GMEC (r2 = 0.61, p < 0.001). The prevalence of S. mansoni infection increased by age to 55.4% (SE +/- 3.2) at age 16, without significant change in the adult ages. There was no gender difference until age six, after which males were consistently higher until middle age, when the differences converged. The age and sex specific pattern of GMEC varied widely, however, when the GMEC data were collapsed into five year age groups, GMEC peaked at 81.5 (SE / + - 12.1) epg in the 10 to 14 year age group. These estimates provide the basis for evaluating control measures for reducing prevalence, intensity of infection, and transmission.
这是一篇关于埃及“流行病学123”项目的早期描述性报告，该项目采用了大样本概率抽样方法。这些结果聚焦于尼罗河三角洲北部卡夫尔谢赫省的曼氏血吸虫感染情况。抽取了一个代表全省农村人口的18777人的概率样本。该样本的设计不基于地理位置或医疗设施的存在来排除村庄，并且纳入了较小的埃兹巴或小村庄的代表。目的是获得关于曼氏血吸虫感染的年龄和性别特异性模式的详细估计，并为前瞻性研究提供基线。粪便标本采用加藤法进行检查。在考虑样本设计的影响进行加权后，44个村庄和埃兹巴的农村人口中曼氏血吸虫感染的估计患病率为39.3%（标准误±3.3）。每克粪便的估计几何平均虫卵计数（GMEC）为72.9（标准误±7.3）。患病率和GMEC在不同村庄和埃兹巴之间差异很大，埃兹巴的患病率显著更高。村庄和埃兹巴的特异性患病率与GMEC密切相关（r2 = 0.61，p < 0.001）。曼氏血吸虫感染的患病率随年龄增长，在16岁时达到55.4%（标准误±3.2），成年后无显著变化。6岁之前没有性别差异，此后男性患病率一直较高，直到中年时差异趋于一致。GMEC的年龄和性别特异性模式差异很大，然而，当GMEC数据合并为5岁年龄组时，GMEC在10至14岁年龄组达到峰值，为81.5（标准误/±12.1）个虫卵/克。这些估计为评估降低患病率、感染强度和传播的控制措施提供了基础。
