González Ipiña M, Roche Herrero M C, López Martín V, Hawkins Carranzo F, Sánchez Purificación M T, Pascual-Castroviejo I
Servicio de Neurología Infantil, Hospital la Paz, Madrid.
Neurologia. 1996 Feb;11(2):51-5.
Benign neonatal convulsions, though rare, are seen with increasing frequency and are characterized by seizures during the neonatal period with favorable prognosis. Two distinct entities can be identified, based on whether the syndrome is familial or non-familial, with epilepsy developing in 14% of patients with the familial form. We report a retrospective study of 23 patients, 13 with benign familial neonatal seizures and 10 with benign idiopathic neonatal seizures. All except one had normal neurologic development. We observed central temporal (rolandic) EEG foci in the follow-up of a few patients in both groups, with no clinical manifestations. We consider the possibility that these entities may share common genetic factors with benign rolandic epilepsy.
良性新生儿惊厥虽然罕见，但出现频率日益增加，其特征为新生儿期发作且预后良好。根据综合征是家族性还是非家族性，可识别出两种不同类型，家族性形式的患者中有14%会发展为癫痫。我们报告了一项对23例患者的回顾性研究，其中13例为良性家族性新生儿惊厥，10例为良性特发性新生儿惊厥。除1例患者外，所有患者神经发育均正常。我们在两组部分患者的随访中观察到中央颞区（罗兰区）脑电图病灶，但无临床表现。我们认为这些类型可能与良性罗兰区癫痫共享共同的遗传因素。
