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[子宫内膜异位症和不明原因不孕症女性中抗核抗体的出现情况]

[Occurrence of antinuclear antibodies in women with endometriosis and unexplained infertility].

作者信息

Malinowski A, Szpakowski M, Wilczyński J, Banasik M, Puchała B

机构信息

Katedry Połoznictwa i Ginekologii WAM w Lodzi.

出版信息

Ginekol Pol. 1995 Jul;66(7):420-4.

PMID:8655009
Abstract

The relationship between female infertility, endometriosis and antinuclear antibodies (ANA) in the blood of women without clinical symptoms of autoimmune disease is described. ANA in the titre of 1:40 and more, was detected in 63% women with endometriosis, 70.4% women with idiopathic infertility, 3.3% women with hypothalamic-pituitary dysfunction and 5.6% healthy nonpregnant women. The occurrance of ANA in endometriosis and idiopathic infertility was more frequently connected with negative postkoital test and the number of spontaneous abortions. We suggest, that (auto)immunological mechanisms play an important role in endometriosis and unexplained infertility.

摘要

本文描述了无自身免疫性疾病临床症状女性血液中抗核抗体(ANA)与女性不孕、子宫内膜异位症之间的关系。在患有子宫内膜异位症的女性中,63%检测到滴度为1:40及以上的ANA;特发性不孕女性中,70.4%检测到;下丘脑 - 垂体功能障碍女性中,3.3%检测到;健康未孕女性中,5.6%检测到。子宫内膜异位症和特发性不孕中ANA的出现更常与性交后试验阴性和自然流产次数相关。我们认为,(自身)免疫机制在子宫内膜异位症和不明原因不孕中起重要作用。

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