Garrison J R, Richardson J D, Hilakos A S, Spain D A, Wilson M A, Miller F B, Fulton R L
Department of Surgery, University of Louisville School of Medicine, Kentucky 40292, USA.
J Trauma. 1996 Jun;40(6):923-7; discussion 927-9. doi: 10.1097/00005373-199606000-00010.
To determine if the decision to pack for hemorrhage could be refined.
Seventy consecutive trauma patients for whom packing was used to control hemorrhage were studied. The patients had liver injuries, abdominal vascular injuries, and bleeding retroperitoneal hematomas. Preoperative variables were analyzed and survivors compared with nonsurvivors.
Packing controlled hemorrhage in 37 (53%) patients. Significant differences (p < 0.05) between survivors and nonsurvivors were Injury Severity Score (29 vs. 38), initial pH (7.3 vs. 7.1), platelet count (229,000 vs. 179,000/mm3), prothrombin time (14 vs. 22 seconds), partial thromboplastin time (42 vs. 69 seconds), and duration of hypotension (50 vs. 90 minutes). Nonsurvivors received 20 units of packed red blood cells before packing compared to 13 units for survivors.
Patients who suffer severe injury, hypothermia, refractory hypotension, coagulopathy, and acidosis need early packing if they are to survive. Failure to control hemorrhage is related to severity of injury and delay in the use of pack tamponade. A specific protocol that mandates packing when parameters reach a critical limit should be considered.
确定针对出血的填塞决策是否可以优化。
对连续70例使用填塞法控制出血的创伤患者进行研究。这些患者患有肝损伤、腹部血管损伤和腹膜后血肿出血。分析术前变量,并比较幸存者与非幸存者。
填塞法控制了37例(53%)患者的出血。幸存者与非幸存者之间的显著差异(p < 0.05)在于损伤严重度评分(29对38)、初始pH值(7.3对7.1)、血小板计数(229,000对179,000/mm³)、凝血酶原时间(14对22秒)、活化部分凝血活酶时间(42对69秒)以及低血压持续时间(50对90分钟)。非幸存者在填塞前接受了20单位的浓缩红细胞,而幸存者为13单位。
遭受严重损伤、体温过低、难治性低血压、凝血功能障碍和酸中毒的患者若要存活,需要尽早进行填塞。未能控制出血与损伤严重程度以及延迟使用填塞止血有关。应考虑制定一项在参数达到临界值时强制进行填塞的特定方案。