Inagaki T, Niimi T, Yamamoto T, Hashizume Y, Ogihara M, Mizuno T, Inagaki A, Kikuchi M
Department of Internal Medicine, Nagoya City Kohseiin Geriatric Hospital, Japan.
Nihon Ronen Igakkai Zasshi. 1996 Feb;33(2):84-94. doi: 10.3143/geriatrics.33.84.
The purpose of this study was to assess the background to the longevity of 36 centenarians in Nagoya city and to compare 14 institutionalized centenarians out of those 36 with 202 individuals in the 70-99 age group in our special nursing home, particularly with regard to blood chemistry and immunity tests. The reasons for their social longevity in terms of profile appeared to be attention to eating habits, abstention from smoking and drinking, occupations with adequate exercise. The incidence of dementia was 65.6% among them. We evaluated centenarians from the viewpoint of Hasegawa's Dementia Scale (HDS) and comprehensive functional assessment of the elderly consisted of the revised version of Hasegawa's Dementia Scale (HDSR), and examination of activity of daily living (ADL), physical perception, and social life. All were positively associated. Thus centenarians independent of physical assistance demonstrated significantly higher systolic blood pressure, and respective scores for HDS, HDSR, ADL, physical perception and social life than their dependent counterparts, were less likely to be institutionalized and suffered from fewer disorders. In particular none were diagnosed as positive for cerebral hemorrhage, infarction and dementia. Age demonstrated significant positive or negative correlation with the following values in blood chemistry and immunity tests: blood cell counts, hemoglobin concentration, hematocrit value, albumin, total protein, total cholesterol, low density lipoprotein cholesterol, creatinine, blood cell nitrogen, uric acid, helper T cell, and IgA immunoglobulin.
本研究旨在评估名古屋市36位百岁老人长寿的背景,并将这36位老人中的14位入住机构的百岁老人与我们特殊养老院中202位70 - 99岁的老人进行比较,特别是在血液化学和免疫测试方面。从个人资料来看,他们社会长寿的原因似乎是注重饮食习惯、戒烟戒酒以及从事有适量运动的职业。他们中痴呆症的发病率为65.6%。我们从长谷川痴呆量表(HDS)的角度以及由长谷川痴呆量表修订版(HDSR)、日常生活活动能力(ADL)检查、身体感知和社会生活组成的老年人综合功能评估的角度对百岁老人进行了评估。所有这些都是正相关的。因此,独立生活无需身体协助的百岁老人的收缩压显著更高,并且在HDS、HDSR、ADL、身体感知和社会生活方面的各自得分比依赖他人的百岁老人更高,他们被送入机构的可能性更小,患疾病的情况也更少。特别是,没有人被诊断为脑出血、脑梗死和痴呆呈阳性。在血液化学和免疫测试中,年龄与以下各项值呈现出显著的正相关或负相关:血细胞计数、血红蛋白浓度、血细胞比容值、白蛋白、总蛋白、总胆固醇、低密度脂蛋白胆固醇、肌酐、血细胞氮、尿酸、辅助性T细胞和IgA免疫球蛋白。