[青年成年人对麻疹、风疹和腮腺炎的易感性]

[Susceptibility to measles, rubella and parotitis in young adults].

作者信息

Bayas J M, Vilella A, Vidal J, Nebot X, Carbó J M, Navarro G, Prat A, Asenjo M A, Salleras L

机构信息

Servicio de Medicina Preventiva, Hospital Clínic i Provincial, Universidad de Barcelona.

出版信息

Med Clin (Barc). 1996 Apr 20;106(15):561-4.

PMID:8656753

Abstract

BACKGROUND

The aim of this study was to know the prevalence of antibodies against measles, rubella and parotiditis in young adults.

METHODS

The study was carried out in health care students during the academic year of 1992-1993. Demographic and geographic variables were obtained as were vaccination and history of diseases. Antibodies against measles, rubella, and parotiditis were determined by ELISA techniques with commercial reagents.

RESULTS

Three hundred and six individuals of 21.3 +/- 2.2 years (range 17-36 years) with 27.5% being males were studied. Past history of measles, rubella and parotiditis was reported in 43.5, 30.7 and 37.3%, respectively, with vaccination being 23.2, 43.8 and 20.6%, respectively. The prevalence of antibodies was 93.1% (measles), 96.4% (rubella) and 92.1% (parotiditis).

CONCLUSIONS

The prevalence of infection of measles, rubella and parotiditis in the young population studied is mainly due to infection by wild type virus. The foreseeable growth of susceptibility groups in this population which should be adequately evaluated by extensive seroepidemiologic questionnaires, favors the appearance of epidemic outbreaks. The use of the triple viral vaccine is suggested as an alternative to rubella vaccination in presumable susceptible young women.

摘要

背景

本研究旨在了解年轻成年人中麻疹、风疹和腮腺炎抗体的流行情况。

方法

该研究于1992 - 1993学年在医护专业学生中开展。收集了人口统计学和地理变量以及疫苗接种情况和疾病史。采用商用试剂通过酶联免疫吸附测定（ELISA）技术检测麻疹、风疹和腮腺炎抗体。

结果

共研究了306名年龄为21.3±2.2岁（范围17 - 36岁）的个体，其中男性占27.5%。分别有43.5%、30.7%和37.3%的人报告有麻疹、风疹和腮腺炎既往史，疫苗接种率分别为23.2%、43.8%和20.6%。抗体流行率分别为93.1%（麻疹）、96.4%（风疹）和92.1%（腮腺炎）。