Fraizzoli G, Sesana B M
Ann Ig. 1989 Sep-Oct;1(5):1163-71.
Immunity status to measles, mumps, rubella and type B hepatitis (HB) viruses was studied in a cohort of 83 teen-agers (13-14 years). The vaccination against these agents is optional in Italy. Out of 83 subjects none had been vaccinated against measles, mumps and HB viruses, while 31 had had rubella vaccination. The percentage of seronegative adolescents was 2% for measles, 25% for mumps and 10% for rubella among unvaccinated teen-agers. These data suggest that even adolescent could be a target for rubella and mumps vaccination. On the contrary HBV does not appear to circulate extensively in the early years of life, so there is no need to extend the vaccination outside the risk groups. The presence of antibodies to measles, mumps and rubella viruses correlated very well with the anamnestic recall referred by the mothers. On the contrary for rubella and mumps viruses there was a high proportion of seropositive subjects with a negative history of disease. Therefore in the population under study asymptomatic infections with rubella and mumps viruses should have been rather frequent.
对一组83名青少年（13 - 14岁）的麻疹、腮腺炎、风疹和乙型肝炎（HB）病毒免疫状况进行了研究。在意大利，针对这些病原体的疫苗接种是可选择的。83名受试者中，无人接种过麻疹、腮腺炎和HB病毒疫苗，而31人接种过风疹疫苗。在未接种疫苗的青少年中，麻疹血清阴性青少年的比例为2%，腮腺炎为25%，风疹为10%。这些数据表明，即使是青少年也可能是风疹和腮腺炎疫苗接种的对象。相反，HBV在生命早期似乎没有广泛传播，因此无需将疫苗接种扩大到风险群体之外。麻疹、腮腺炎和风疹病毒抗体的存在与母亲提及的既往回忆高度相关。相反，对于风疹和腮腺炎病毒，有相当比例血清阳性的受试者没有疾病史。因此，在所研究的人群中，风疹和腮腺炎病毒的无症状感染应该相当常见。
